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July 8, 2009

Opinion - Grid technologies in Latin America

Senator Jefferson Praia.
Image courtesy BELIEF II.

To find out what the speakers at the upcoming BELIEF (Bringing Europe’s eLectronic Infrastructures to Expanding Frontiers) International Symposium think about the state of e-infrastructure in Latin America, we interviewed Senator Jefferson Praia, who is also a professor at Amazonas University, Brazil. He shared his thoughts on grid technologies in the region.
What do you do?I am a Brazilian Senator representing the Amazonas State. This House plays an important role in the Senatorial Committee of Environment and Control and Fiscalization and the Congressional Committee of Climate Changes, defending the sustainable development in the Congress decisions.What is the current status of grids and e-infrastructures in Latin America?Since the emergence of new technologies in the ’90s, an increasing use of e-infrastructures has been observed.Do you think it is important for Latin Ameri

July 8, 2009
Opinion - South Africa grid: a view from the coordinator's chair

Feature - SAGrid: A view from the coordinator’s chair

SEACOM is a 1.28Tbps, 15,000 kilometer-long undersea fiber-optic cable system that will provide high-speed communication between East Africa, South Asia and Europe. As of press time, its promoters expect the system to be up and running in less than three weeks. Image courtesy SEACOM

Bruce Becker of the Meraka Institute in Pretoria is the Coordinator for planning the upcoming South Africa Grid initiative — which will draw upon the resources of South Africa’s Center for High Performance Computing and the country’s high-speed network, SANREN. Here, he gives an update of the status of the project.After over a year of training sessions and technical workshops in multiple countries, preparations are under way for a move to full production readiness of the South Africa Grid, or SAGrid.The testing and incubation phase is coming to an end; the high-speed national research network SANREN is under way and already ac

July 1, 2009
Feature - Cancer knowledge cloud for a new generation of medicine

Feature - Cancer Knowledge Cloud for a new generation of medicine

Kenneth Buetow, shown speaking at a conference in 2005.Image courtesy of NCRI.

Kenneth Buetow is the National Cancer Institute’s Associate Director of Bioinformatics and IT, and Director of the Center for Biomedical Informatics and IT, where he initiated and oversees the caBIG (cancer Biomedical Informatics Grid) program. He spoke last April at the Bio-IT World conference on caBIG: An interoperable IT framework for uniting research and care.
Thinking BIGKen Buetow thinks BIG.  He envisions what he calls a Cancer Knowledge Cloud — an IT environment designed to foster information connectivity among cancer patients, cancer researchers and clinical care providers. This environment, powered by caBIG tools and infrastructure, would enable a continuous and accelerated cycle of discovery, diagnostic and pharmaceutical product development, and improved clinical care.Cancer care and research still operate on a lin

July 1, 2009

Feature - EVO powers communication for global collaborations

Image courtesy caltech.edu.

For the Large Hadron Collider collaborators who are spread across the globe, staying connected presents challenges. The Enabling Virtual Organizations (EVO) system, a worldwide network designed for institutions participating in the LHC experiments and other high-energy physics collaborative programs, makes international collaboration easier by providing a reliable and secure system for real-time virtual meetings.
EVO, winner of the 2009 Internet2 IDEA award for applied advanced networking “at its best,” hails from the California Institute of Technology (Caltech). In 2008 it hosted more than 9,100 virtual LHC collaboration meetings with a total of over 4,200 users. The combined time each user spent in EVO LHC meetings last year totals more than 86,300 hours. Unlike commercial networks, EVO poses no restriction on the number of participants in a meeting. On September 10, 2008, about 1,250

July 1, 2009
Feature - Grid makes a SPLASH in underwater archaeology

Feature - Grid makes a SPLASH in underwater archaeology

Up to 3.2 million square kilometers of the European continental shelf (about 40 per cent of Europe’s land mass) was exposed as dry land during the periods of lower sea level that persisted throughout the Ice Ages. These now-submerged coastal regions probably played a key role in the survival and dispersal of Europe’s earliest Stone Age inhabitants, the extinction of the last Neanderthals, their replacement by modern humans originating from Africa, and the initial dispersal of agriculture from the Near East. (Insets show local river patterns on the shelf.) Image courtesy Nic Flemming/SPLASH

Submerged beneath the waves lies a large part of human history. For our ancestors, the ancient coastlines were attractive places to settle and experiment with what became the foundations of civilization. As the major glaciers melted between sixteen and six thousand years ago, these sites — where people first began to make fishin

June 24, 2009
Feature - Plenty more fish in the sea?

Feature - Plenty more fish in the sea?

According to the UN’s Food and Agriculture Organization, over 70% of the world’s fish stocks are fully exploited, overexploited or depleted. Image courtesy nahpets/stock.exchng 

Once thought to be an endless source of bounty, the oceans’ supply of fish has plummeted dramatically. The biggest cause of this deterioration — bigger than pollution — is overfishing.
Rampant over-fishing around the globe has caused some of our favorite species to hover near collapse. There has been a 90 percent drop in the number of tuna, salmon, cod, swordfish, rays, pollack and haddock since the 1950s, wrote Jeremy Jackson, director of the Scripps Center for Marine Biodiversity and Conservation at the University of California, San Diego, in a paper published last year in the Proceedings of the National Academy of Sciences.
The effects of over-fishing are being exacerbated by global climate change, which changes the distribution of sp

June 24, 2009
Feature - Watch near real-time earthquake simulations

Feature - Watch near real-time earthquake simulations

(Click image for more information on the topographical map and to see cross-sectional diagrams of compressional wave speed.)
Every time an earthquake occurs in Southern California, thousands of seismograms are recorded at hundreds of seismic stations. The Caltech team collects these seismic recordings automatically from the Southern California Seismic Network (SCSN) through the internet. They subsequently simulate the seismic waves generated by the earthquake in a 3-D  southern California seismic velocity model using the source parameters determined by the seismic network. At periods of about 4 seconds and longer, the resulting wave motion simulated at most stations closely match the gathered data recorded at these stations. Image courtesy of Caltech; image previous page courtesy of Nate Brelsford, stock.xchng

When an earthquake rumbles through southern California, seismometers at almost 400 sites jump into action. They s

June 24, 2009
Opinion - The age of citizen cyberspace

Opinion - The age of citizen cyberspace

Using LHC@home, particle beam dynamics can be studied with volunteer computing. Image courtesy CERN

(François Grey, one of the key people behind the founding of the present-day iSGTW and a frequent contributor to these pages, argues that with volunteer computing, we are about to embark upon a new era of “citizen science.”)
I first met Rytis Slatkevicius in 2006, when he was 18. At the time, he had assembled the world’s largest database of prime numbers — those which are only divisible by themselves and one.
He had done this by harnessing the spare processing power of computers belonging to thousands of prime-number enthusiasts, using the internet. 
Today, Rytis is a mild-mannered MBA student by day and an avid prime-number sleuth by night. His project, called PrimeGrid, is tackling a host of numerical challenges, such as finding the longest arithmetic progression of prime numbers (the current record is 25). P

June 17, 2009
Feature - Coming: Sustained petascale computing for open science

Feature - Coming: Sustained petascale computing for open science

Illinois' Petascale Computing Facility (PCF), which will house Blue Waters, is planned as a leading edge, energy-efficient facility capable of housing multiple Blue Waters-scale systems.  The PCF will provide up to 20,000 square feet (about 1900 m2)and 24 MW for computer equipment (not counting cooling infrastructure) and is  expandable  to two to four times that.
Some of the innovative, energy-saving technologies in the building include 480V power (saves 5-10% in transmission loss), liquid cooling for computational components, and outside ambient air cooling for most of the year to avoid using artificially chilled water.
Image courtesy of NCSF.

Computing capacity has grown dramatically over the last decade, allowing scientists to tackle much larger and more complex research problems. The first sustained petascale computing system for “open” science — science done using open source to

June 17, 2009
Feature - Grid-enabled virus hunting

Feature - Grid-enabled virus hunting

3D replica of senecavirus, a pathogen discovered several years ago by researchers in Pennsylvania. UC San Francisco researcher Eric Delwart and his colleague Chunlin Wang of Stanford University use the RENCI-developed TeraGrid Science Gateway and the Open Science Grid to access grid computing resources in their search for new viruses.
Image courtesy of the Institute for Animal Health, UK

Researchers use distributed computing to make sequence analysis faster and easier.DNA sequencing and sequence analysis happens daily in many biological sciences laboratories, but analyzing large sets of genetic data increasingly requires computing resources beyond the capabilities of most labs. The search for the best hardware and software led Eric Delwart, a professor of laboratory medicine at the University of California, San Francisco, and a senior investigator at the Blood Systems Research Institute, and Chunlin Wang, a research associate at the Stanford Univ

June 17, 2009
Feature - Swine flu and the grid: A researcher's view

Feature - Swine flu and the grid: A researcher’s view As the name suggests, “Swine Flu” may have its origins among pigs, and then may have made the jump across species to humans. Image courtesy Janne Brodin, stock.exchng (Editor's note: Swine Flu — or H1N1 influenza A — has been in the headlines lately. The World Health Organization has officially classified the latest outbreak a “pandemic,” in response to its world-wide geographic spread. To find out more about how the grid fits in with research to fight this virus, we asked Ana Lucia Da Costa of HealthGrid, who formerly worked at CNRS France, to give her viewpoint from the lab.) The emergence of a new influenza epidemic such as this is an opportunity for the grid to contribute to international public health response. It has highlighted the importance of providing the right information to decision-makers as quickly as possible. Grid technology is particularly well fitted to

June 10, 2009

Feature - Do more with MATLAB

Using MATLAB on EGEE middleware, researchers can make a better laser - such as this solid state Cornellium Cn3+ laser created by a sapphire crystal. Image courtesy MATLAB Central

Researchers from disciplines as far apart as lasers and finance have a new computing tool at their fingertips: MATLAB can now run on Enabling Grids for E-sciencE (EGEE) computing power. The software is a high-level language and interactive environment that enables users to perform computationally intensive tasks faster than with traditional programming languages such as C, C++, and Fortran. Widely regarded as a  powerful piece of simulation software, for use in everything from optimizing rocket launch control settings to vector analysis, it is now fully compatible with any grid computing system using gLite middleware.“Our motivation for incorporating this tool was rather straightforward. MATLAB is one of the most popular and important general-purpose scientific software

June 10, 2009
Feature - TeraGrid's Campus Champions: connecting campuses to national HPC

Feature - Campus Champions: Users get help from a familiar face

A few words from Kay Hunt, pictured above . . .In the fall of 2007, Scott Lathrop asked me to work on a new effort to support campus representatives (Champions) across the nation who would become the local source of knowledge about high performance computing opportunities for researchers and educators.After working on the design and development of the project I really became enthused about making contacts all over the United States and developing a network of folks who could learn and grow with each other for the common goals of the group.Now, as lead of the Campus Champion program, I recruit Champions and provide them with timely information, user support, training, resource allocations, and outreach support. There are many who help with these activities — I coordinate the people and the process and do the bulk of the recruitment. I am like the head coach of a basketball team.Off the job, I am a “sportsaholic”

June 10, 2009
Opinion - Grids, clouds and communities: an Open Grid Forum perspective

Opinion - Grids, clouds and communities: an Open Grid Forum perspective

Image courtesy BELIEF

(Editor’s note: Below, Open Grid Forum’s Paul Strong and Craig Lee give their view of the future of grids and clouds.)
OGF’s initial focus on grids has broadened over time, reflecting evolution in community needs and in technologies such as virtualization and cloud computing.
Grids have been widely adopted across academia and industry. Their evolution and deployment has been driven by several desires: to share data and computational resources, to get results faster, to improve efficiency and to collaborate.
Clouds are driven by different needs, primarily the desire for financial flexibility, offered by platforms such as “pay-per-use,” and business agility, such as reduced time to market and the ability to engage in fast, low-risk experimentation. The cloud model relies on the provider first achieving economies of scale, through sharing resources, and then offer

June 3, 2009

Feature - Amoolya Singh, computation and biology

Amoolya Singh in her office at EMBL.  All images courtesy of SET-Routes

Editor's note: Readers may recall our series on women in grid computing last March. ISGTW interviewed more enterprising, trailblazing women in science and computing than our month-long series could accommodate! We will continue to bring you these and other personal profiles occasionally.
iSGTW: What do you do?
Amoolya Singh: I'm a computational biologist at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, which is a fancy way of saying I use computers to understand living things. 
iSGTW: How did you get interested in this field?
Singh: My interest in science has been mainly shaped by my family origins. I was born and raised in India, in a family of scientists and artists. I remember at the age of five going with my mother to her laboratory and asking what she did. She explained that she took very detailed pictures of the insides o

June 3, 2009
Feature - Clarity in clinical care

Feature - Clarity in clinial care: achieving fully interoperable databases

Werner CeustersImage courtesy of W. Ceusters.

Werner Ceusters, director of the  Ontology Research Group at the NYS Center of Excellence in Bioinformatics & Life Sciences, spoke at the Bio-IT World Conference in Boston this past April on the topic of "Do Healthcare IT Standards Hamper the Advance of Science?" 

“Swimming is healthy and contains eight letters.” Absurd? Of course — the real thing is confused with its symbolic representation. Absurdity, then, abounds in current Electronic Health Records (EHRs) according to Werner Ceusters of the New York State Center of Excellence in Bioinformatics and Life Sciences and the University at Buffalo. A polyp by any other name… A significant and universal problem with legacy EHRs, Ceusters says, is that software programs that access them cannot adequately differentiate between diagnoses for a given patient and link them prope

June 3, 2009
Feature - Grid computing promotes diversity in biotech

Feature - Grid promotes diversity in biotechnology at Virginia State

Image courtesy of VSU, Biology department.

Biotechnology is one of the fastest-growing sectors in science, but it suffers from a lack of diversity in its workforce, as do many other scientific fields.  Recent studies* suggest that African-Americans and Hispanics lag behind whites for higher-paying biotech jobs by the largest margins in about a decade.Researchers at Virginia State University, an institution designated by the U.S. Department of Education as one of the Historically Black Colleges and Universities (HBCU), are addressing this imbalance by using grid technology as a resource to teach students and educators about bioinformatics.  Glenn Harris, an assistant professor in the Department of Biology at VSU, used grant funding from the U.S. Department of Agriculture and the National Institutes of Health to obtain a 12-node cluster server and the iNquiry bioinformatics software suite developed by The BioTe

May 27, 2009
Feature - ETICS offers help to software professionals

Feature - ETICS 2 offers help to software professionals

Image courtesy ETICS 2

Software professionals have been know to describe the task of building, configuring and integrating new software in as little as two words: “nightmare activity.”  But with E-infrastructure for Testing, Integration and Configuration of Software Phase 2, or ETICS 2, they have an all-in-one solution that helps configure and build software, and at the same time check its quality. The result of three years of project activities, this system provides tools and resources to build and test runs, thereby simplifying complex and often repetitive activities.
“By automating many day-to-day tasks, ETICS 2 supports software professionals obtain higher quality software, a shorter time-to-market, a lower risk on schedule and reduced project costs,” says Alberto Di Meglio, ETICS 2 project manager at CERN.
The ETICS 2 system exploits grid software and distributed computing infrastructures. It is

May 27, 2009

Feature - Gridding the aerosol problem

Image courtesy BEinGRID

It can be difficult to measure the number of aerosols – tiny particles suspended in the air – that are in our planet’s atmosphere.Such knowledge is important in a number of ways, as aerosols can have an effect upon everything from short-term  air-quality forecasting to predicting the effects of aerosols on global warming. At least one climatologist says that on a long-term, global scale, aerosols will make India’s monsoons more intense, and Australia’s droughts hotter and longer. So, wet areas will be wetter, and dry areas drier. (See 7 January 2009 iSGTW, “Opinion - UK grid researchers aid efforts to understand climate change.”) Tracking where aerosols come from, where they tend to collect, and where they tend to “sink” on a planetary scale is a tricky business as well . Due to wind and weather patterns, sometimes the most pristine, remote areas accumulate the most

May 27, 2009

Feature - Volunteer computing against childhood cancer

Image courtesy of WCG.

Researchers from the Chiba Cancer Center Research Institute and Chiba University in Japan are launching a new World Community Grid project with IBM to discover a drug treatment for neuroblastoma, the most common cause of death in children with solid tumors. Help Fight Childhood Cancer, as the project is known, uses idle computational power from volunteers’ home and office computers to identify promising drug candidates.Most physicians believe that neuroblastoma is caused by accidental cell growth that occurs during normal development of the sympathetic ganglia and adrenal glands. This condition occurs most often the first two years of life, and poses a high risk for disease relapse with survival rates under 40 percent.The new Help Fight Childhood Cancer project uses volunteered computational power to identify which of the three million potential drug candidates prohibit growth of three proteins, TrkB, AL

May 20, 2009

Feature - A side of cloud with your grid, ma’am?

Belle II co-spokesman Masanori Yamauchi (left) with 2008 Nobel prize winner in physics Makoto Kobayashi.Image courtesy of Belle II.

As the cloud becomes a more popular computing solution in the commercial world, it is starting to pique the interest of the academic research community. Collaborators of the Belle II experiment at the High Energy Accelerator Research Organization, known as KEK, in Japan are considering supplementing their computing with Amazon’s Elastic Compute Cloud (EC2), which provides on-demand, virtual computing resources over the Internet. The KEKB particle accelerator produces a more densely-packed, intense beam than any currently operating collider, and an upgrade to the machine in 2013 is expected to increase the intensity by a factor of 50. The new Belle II detector will come online at the same time equipped to handle the estimated hundred-fold increase in data — expected to total 40 petabytes per

May 20, 2009
Feature - Countdown: World's most sophisticated thermometer blasts off into space

Countdown! World’s most sophisticated thermometer blasts off into space

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Arianespace sent into orbit a scientific satellite known as the Planck scientific observatory, for the European Space Agency.  The launch process took the new instrument from the ground into space in less than an hour. Image courtesy ESA

On 1:12 pm on Thursday, May 14, the Planck satellite — arguably the world’s largest thermometer — lifted off from the European Space Agency’s launch pad in French Guiana.
The launch began with a 6-second vertical climb. The onboard computers optimized the motion of the rocket in real time, in order to minimize fuel consumption. The main stage engine took the launcher into an intermediate orbit before the end stage carried the payload into the final orbit. The main stage of the launcher fell back, just off the coast of Africa in the Atlantic Ocean. The launcher will remain at an altitude of about 852 kilometers travelling at about

May 20, 2009

Feature - Identifying network bottlenecks Internet2 and the Open Science Grid have formed a partnership to deploy advanced network monitoring and diagnostic tools on the grid. Image courtesy of invoice-factoring.com.au. Network performance problems bedevil scientists and network operators alike.  Troubleshooting requires a multi-pronged approach, and problem resolution often drags – holding back scientific progress. To address this in the grid community, Internet2, the leading U.S. networking consortium in the research and education community, has formed a partnership with the Open Science Grid to deploy a set of advanced network monitoring and diagnostic tools on the grid.Network users and operators solve problems most quickly when given transparent access to the entire network path involved. Typically, however, separate organizations operate different segments along a full network path and each so-called “domain” controls access to its own diagnostic and p

May 13, 2009
Feature - EDGeS helps us all talk to each other

Feature - EDGeS helps us all talk to each other

With AutoDock, biologists can predict how small molecules will interact with known larger molecules - vital to evaluating candidates for new drugs. Image courtesy www.YASARA.org

Like Bill Murray adrift in Japan in the movie “Lost in Translation,” things can go awry when service grids and volunteer grids try to talk to each other.
Service grids, such as EGEE, often involve large institutions whose work method is centered around collaboration — to the point where participants often know each other personally. To ensure security, resources and users pass through an accreditation process, and the resulting “certificate” provides proof that this occurred successfully. The certificate is key to allowing jobs to be submitted and completed.
On the other hand, volunteer systems — such as BOINC or XtremWeb-based desktop grids — consist of large numbers of personal computers linked together by individuals w

May 13, 2009

Feature - Peking University advances protein research

At top: Superimposition of 20 structures of hPHPT1. At bottom: Ribbon diagram of the mean structure of hPHPT1. Red: alpha-helix, blue: beta-sheet, white: random coil. Image courtesy of Weibin Gong

Researchers at Peking University’s Beijing Nuclear Magnetic Resonance Center (BNMRC) can determine 3D protein structures 1000 times faster, thanks to the grid. 
Function follows form in the protein world, so their work contributes to scientists’ understanding of the roles that individual proteins play. This in turn should lead to advances in drug discovery and health care.The Peking University team uses Nuclear magnetic resonance (NMR) spectroscopy to determine protein structures. NMR works well, but the calculations involved are time-consuming and computationally demanding. Scientists have so far learned the structure of only about 50,000 proteins out of the millions that exist in nature.
The Peking team has calculat