iSGTW - International Science Grid This Week

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Issue 73: iSGTW 07 May 2008

WISDOM unplugged: malaria drug-leads graduate to the wet lab

After screening one million candidates, WISDOM’s grid-powered research collaboration selected just 30 individuals to go through to the next round. Tipped to inhibit the deadly action of malaria protein plasmepsin, these 30 molecules hold hope for millions of malaria sufferers.

So how did the WISDOM candidates perform off-screen? Can grid computing really shortcut the drug discovery process?

Feature - Particle physics

Testing the limits of the Standard Model
How far does the Standard model of physics stretch? Is there a new physics, and where does it begin?

Questions about the Standard Model have stymied scientists for decades, but Robert Sugar believes we’ll have answers in just five to ten years.

Feature - Cell biology

Cell biologists dig new DiGS
In a bid to beat the data deluge, cell biologists are adopting data management software developed by physicists.

Called DiGS, or Distributed Grid Storage, the software is on trial at the Universities of Edinburgh and Oxford, supporting an investigation into the transport and anchoring of mRNA in Drosophila flies.

Link of the week

Old friends and new: iSGTW, GridCafé, GridTalk and more
It’s “Hello!” “Goodbye!” “Hello!” in the iSGTW office as we welcome a new editorial team, farewell outgoing editor Cristy Burne, and then welcome her back as part of new project GridTalk.